Archives of Hellenic Medicine

Last update:

25-May-2026

Arch Hellen Med, 43(Supplement 1), 2026, 76-81

ORIGINAL PAPER

Comparison of fatigue among chronic kidney disease patients on hemodialysis
and continuous ambulatory peritoneal dialysis in Indonesia

A. Rifai,¹ A. Gunawan,¹ I.A.D. Satiti²
¹Division of Nephrology and Hypertension, Department of Internal Medicine, Universitas Brawijaya, Malang
²Department of Internal Medicine, Universitas Brawijaya, Malang, Indonesia

OBJECTIVE To assess the difference of fatigue in patients with chronic kidney disease (CKD) undergoing hemodialysis (HD) versus continuous ambulatory peritoneal dialysis (CAPD) in Indonesia.

METHOD This cross-sectional study was conducted at Saiful Anwar Hospital Malang, Indonesia between August 2024 and January 2025. Data were collected from the Fatigue Severity Scale (FSS) questionnaire, demographic data, and laboratory results. Statistical analyses included Chi-square, Mann-Whitney, and multivariate analysis for differences and fatigue-associated factors.

RESULTS This study included 139 CKD patients, of whom 50 on CAPD and 89 on HD. The prevalence (p=0.0233) and severity (p=0.021) of fatigue were found to be higher in the CAPD group than in the HD group. Hemoglobin level (p=0.005) and age (p<0.001) were significantly linked to fatigue in the HD group, whereas employment status (p=0.013), age (p=0.017), and hemoglobin level (p=0.015) were significant factors in the CAPD group.

CONCLUSIONS Hemoglobin level, age, and work status are significant determinants of fatigue risk in CAPD patients, which is higher than in HD patients. These results emphasize the necessity of tailored and interdisciplinary strategies for CKD patients' fatigue management.

Key words: Anemia, Chronic kidney disease, Fatigue, Hemodialysis, Peritoneal dialysis, Quality of life.