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24-May-2026
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Arch Hellen Med, 43(Supplement 1), 2026, 114-119 CASE REPORT Post-treatment wound healing with gel, serum, and cream formulations A.I. Putri,1 M.Y. Listiawan,2 A.D. Prasetyo,1 V. Adiningtyas,3 M.A. Rubianti,4 I. Rosellini5 |
A 37-year-old woman with Fitzpatrick skin type IV presented for wound healing evaluation following a fractional CO2 laser procedure. She experienced erythema, slight edema, and stinging on the face post-procedure. The patient had no history of chronic skin disease, keloids, or sensitivities to topical ingredients. Physical examination revealed mild to moderate erythema without signs of infection. The patient received wound care using topical therapy with panthenol, madecassoside, and thermal spring water in cream, gel, and serum, against a control with panthenol moisturizer. Clinical evaluation using VISIA® camera system found that the treatment side resolved erythema and edema faster than the control side. Although there were short-lived eruptions of acneiform nature, no serious side effects occurred, and there was increased patient satisfaction with the intervention products. In conclusion, topical formulation with panthenol, madecassoside, and thermal spring water was effective for wound healing after fractional CO2 laser treatment and was comparable to usual moisturizers regarding increased patient satisfaction.
Key words: Fractional CO2 laser, Panthenol and madecassoside, Post-treatment wound healing, Skin recovery and inflammation, Topical formulations.