Last update:
11-Jul-2004

Arch Hellen Med, 2000, 17(Supplement):44-50

LECTURE

The pathogenesis and laboratory findings of atherosclerosis
from hemostasis standpoint

O.N. ULUTIN
Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey

In a brief review, the pathogenesis of atherosclerosis, as related to the mechanism of hemostasis, is discussed. The types of disorders that have been noted concerning the hypo- and dys- function of the endothelium, the decrease of fibrinolytic activity, the increase of several coagulation factors, the decrease of natural inhibitors and the proliferation and migration of smooth muscle fibers are extensively described. The findings of the author and his colleagues are presented.

Key words: Atherogenesis, Atherosclerosis, Hemostasis, Platelets.